Valin in which vitamins is contained. Valin

Valin is an aliphatic (branched) amino acid, which is part of 70% of proteins, but not synthesized by the body. Performs a matrix of pantothenic acid synthesis (vitamin B5) and penicillin (valinecin). The value of this amino acid is difficult to overestimate: the body is not capable of working fully without L (L) and D (D) valine isomers, since it is they supply the energy used in muscle tissue, and is responsible for the possibility of body movement in space.

Characteristic

For the first time, Valin was obtained in the laboratory conditions in 1901 by the German chemist Emil Fisher in the casin hydrolysis. Named in honor of Valerians because it participates in stimulating the activity of the body, thereby maintaining its structural integrity.

In terms of its characteristics, Valin is reminded of isoleucine. This hydrophobine amino acid, therefore, almost inert to chemical and biochemical processes in the body, but at the same time determines the three-dimensional proteins and can absorb other amino acids.

Valin is also called the glucuen amino acid for the ability of its isomers to transform into the liver in glucose - the most affordable energy source for muscles. In parallel, vitamin B3 is synthesized from the isomers of the valine.

Pharmacological properties

The very name of the amino acid says that its main property is influence on the CNS with adjusting braking and excitation processes.

In addition, she:

• manifests a stimulating effect;
• enhances regeneration processes in the body;
• increases the endurance of tissues to external influences;
• opposes stress and mental overvoltage;
• actively counteracts the development of alcohol and drug addiction;
• balans metabolism, reducing appetite and contributing to weight loss;
• reduces the threshold of pain sensitivity, especially when exposed to the temperature factor;
• regulates the production of growth hormone, hemoglobin, nitrogen concentration in the body;
• improves condition with common sclerosis.

Daily need

A person per day is about 2-4 g of valine. The exact dosage is calculated by the formula: 10 mg of amino acids per 1 kg of body weight. If you need to increase the dose for the reference point, not 10, but 26 mg of biologicality is taken.

Remember that when taking the preparations of valine, any dose calculations are conducted by the doctor, since the compound has serious contraindications for receiving and can bring not only the benefit, but harm. In case of insufficiency of the function of the liver or kidney, hemolytic anemia, diabetes, the pathology of the gastrointestinal tract, the use of amino acids is limited.

Food sources

Since the valine is an indispensable amino acid, its concentration in the body depends solely on receipt along with the products. Top amino acid content in food correlations with nutritional value is presented in the table.

100 g of product	Amino acid in mg.
Cheese: Parmesan, Edam, Goat, Mel, Swiss	2500
Cottage cheese, eggs, milk, yogurt	2400
, legumes, nuts, corn	2000
Sea cabbage, seafood	1950
Meat (except pork)	1900
Bird, Fish (except Tuna), Pork (Cut)	1600
Pumpkin seeds	1580
	1500
Mushrooms, Wild Rice, Grech,	400
Whole grains	300

The easiest of all is digested by B5 and out of nuts and eggs.




Indications

• under depressive states, sleep disorders;
• migraine;
• as a component in the treatment of alcoholism and narcotic dependence;
• with physical overvoltage;
• its deficiency in the body;
• excess weight;
• functional disorders in the food and urinary system;
• detoxification;
• injuries with impaired tissue integrity.



Contraindications

Valin is always prescribed after clinical and laboratory surveys and contraindicated in the case of:

• severe disorders of the liver function, kidneys, heart;
• pregnancy and breastfeeding;
• if the patient is up to 18;
• diabetes, hepatitis, metabolic disorders;
• individual intolerance.

Side effects

In the case of overdose, there are symptoms of intoxication: nausea, temperature rise, vomiting, rapid heartbeat, delirium.

The lack of villine is manifested by weakness and increased fatigue, disruption of the concentration of attention.

Interaction with other substances

With a combined reception of a substance with other drugs, it is necessary to take into account its features:

• amino acid is always accepted with leucine and isoleucin (the dosage is calculated by the doctor);
• valin is never used simultaneously with tryptophan and tyrosine, since it reduces their penetration into brain cells;
• the amino acid is perfectly absorbed while eating - with porridge,

The important properties of the amino acid of the valine are revealed, how to receive and in which products are contained.

Amino acid valine third closing element important sports additive Before that, the first 2 elements and are considered.

I do not want to repeat, but it should be reminded that Valine refers to the family of essential amino acids, it is not produced by the body, but comes with food. It includes an elevated protein content, besides this, the valine is the basis for the formation of a group of vitamins B5, which helps with physical fatigue and during the period of stress.

Properties Valina

1. Supports serotonin and improves protein assimilation- When the body is minimized in the body, the proteins begin to collapse, it immediately affects the size of the muscles, which is the most negative for sports, other newly admitted proteins when it is deficient is starting worse.

Also, this amino acid is used often in medicine to eliminate depression, as it increases serotonin in the body, and this is known as a hormone of joy.

2. Holds a nitrate balance - For fitness and bodybuilding, the creation is worth the first priority beautiful figure Through a set of muscle mass so that it is necessary to increase the nitrate balance, valine and, including the entire BCA complex contributes to this.

3. Takes part in creating energy - Valin helps strengthen muscle contractions, thanks to which the coordination of muscles increases, it all happens through the use of amino acids to splash energy into the body, also itself, as isoleucine and leucine.

4. Restores recovery - The deficiency of this amino acid slows down the body, which in turn reduces the speed of absorbing with muscle tissues with muscle tissues, it all affects both the rate of deliverance from subcutaneous and to increase the volume of the muscles.

5. The effect of cortisol - Valin is important to reduce catabolic processes that enemy No. 1 for muscles, he tries to actively destroy them, believing that this is an extra element of the body. Do not even visit gymYou can increase performance and reduce fatigue due to the reception of this sports additive.

In which products contains valine

It can be found in the following foods:

Salmon fillets

Chicken fillet

Beef

Boby

Chicken eggs

Milk

How to take Valin

For ordinary people who are physical activity in a burden, doses within 2-4g. Every day, for actively engaged in sports, its dosage should be increased from 4 to 12gr., the best effect is achieved when receiving the entire complex of the ACA.

You need to take a dose of 2 equal parts 30 minutes before the start of the training and after the training. If you need more quickly recovery, it will help for this additional admission of amino acids.

Valin belongs to the group of amino acids with an extensive structure of the molecule. These substances are approximately 70 percent of all proteins in the human body.

However, this amino acid is not produced by the body, therefore it should be supplied with food or biodevices.

general characteristics

In 1901, the German chemist Emil Fisher, by hydrolysis of proteins, for the first time allocated Valin from Casin. This amino acid is owned by Valerian. Today, this substance is known as an indispensable amino acid, which stimulates the activity of the body, contributes to the formation and maintenance of its structural and functional integrity.

Valin is an aliphatic amino acid, which has a non-polar character. Closely associated with leucine and isoleucine, which has a number of common properties. These hydrophobic substances rarely take part in biochemical reactions, but play a crucial role in determining the three-dimensional structure of proteins. In addition, Valin contributes to the absorption of other amino acids.

Valin (L and D isomers) is also known as glucuine amino acid. That is, if necessary, the liver is capable of transforming this substance in glucose, which the muscles are then used as an additional source of energy. In addition, serves as the original "material" for synthesis and penicillin.

Role in the body

Valin is an important substance to maintain the functions of the body, in particular the health of the muscles and the immune system.

Prevents damage to muscles and supplies fabric with additional glucose necessary to generate energy during physical activity. In combination with isoleucine and leucine, it contributes to normal growth, tissue restoration, regulates blood sugar levels, and also provides the body with energy.

This indispensable amino acid is significant for the central and vegetative nervous system, is important for the adequate flow of cognitive functions, it is necessary for the proper operation of the psyche. In addition, it is a substance that is inhibiting Triptophan transport through the hematorecephalic barrier.

Valin is important for the liver. In particular, it derives from the authority to potentially toxic excess nitrogen. It also helps in the treatment of the gallbladder, liver (with cirrhosis, hepatitis C) and other organs affected by alcoholism or drug addiction. It is an effective prophylactic agent against encephalopathy or brain damage caused by excessive alcohol consumption. It has antiviral properties. He is the predecessor of Penicillin.

Functions and Benefits Valina

Valin has many advantages. This amino acid is a real salvation for people suffering from insomnia and nervousness. The effectiveness in the treatment of muscles and the regulation of the immune system is also proved. And those who want to lose weight take this substance as a means of excessive appetite.

Other properties of Valina:

1. An indispensable amino acid, which has a stimulating effect, is necessary for muscle metabolism, growth, tissue restoration and proper coordination.
2. Being glucoamine acid, provides an additional glucose organism.
3. Useful for the treatment of liver and gallbladder.
4. Helps to adjust the balance of amino acids in the body (for example, during drug addiction).
5. Promotes mental activity, supports a calm mood, eliminates depression.
6. Important to regulate nitrogen concentration in the body.
7. Before hitting the bloodstream, not processed by the liver.
8. In high concentrations are contained in muscle tissue.
9. Any acute physical stress, as well as surgical interventions, are the reason for increasing the daily rate of valine, leucine, isoleucine.
10. Ensure to get rid of alcohol and narcotic dependence.
11. Improves the condition with multiple sclerosis.
12. We need people with increased sensitivity to temperature modes.

Valin for bodybuilders

But, perhaps, the most advantages of Valina are experienced athletes, in particular bodybuilders. For athletes, this amino acid is important as a substance for the restoration of muscle tissue, accelerate metabolism and increasing endurance. Bodybuilders use valine together with and leucine, which contributes to a more rapid muscle growth, supplying additional energy. In addition, the amino acid helps a light recovery after injuries or overvoltages.

Daily need

The waste need for Valina is approximately 2-4 g.

A more accurate individual dosage can be calculated by the formula: 10 mg of amino acids per 1 kg of weight (or 26 mg of substance per 1 kg - when it is necessary to increase the dose).

However, faces with liver or kidney dysfunction should not be used in the form of a biojugant without consulting a doctor. High doses of amino acids can aggravate diseases. Also reduce the intensity of the consumption of the valine should be persons with diseases of the gastrointestinal tract and in the presence of a sickle-shaped anemia. But diabetes, diseases of the gastrointestinal tract, insufficient developing enzymes, on the contrary, worsen the absorption of amino acids.

Amino acid deficiency

Despite the fact that the valine reserves are easy to replenish from food, there are cases of amino acid deficit. The disadvantage of this substance affects the quality of myelin (shell nerve cells), as well as the cause of degenerative neurological diseases. The lack is manifested in the form of the so-called "maple syrup" disease (there are people whose body is not able to absorb leucine, isoleucine and valine). The unusual name of the ailment is explained very simply: these patients urine acquires the smell of maple syrup.

In addition, the experiment on rats showed that with a lack of valine in the tissues of the liver, lipid formations appear. Also, hair loss, weight loss, growth stop, leukopenia, or hypoalbuminemia, may indicate a shortage of amino acids (the level of albumin levels in the blood is sharply reduced. Also possible damage to the mucous membranes, arthritis, problems with memory, depression, muscle atrophy, sleep disorders, weakened immunity.

People, in whose diet, not enough protein food, as well as persons professionally engaged in sports, to avoid the deficit of the valine must take care of its additional admission in the form of bio-support.

Overdose: What is the danger

Vallan intake in too high doses can lead to hallucinations and a feeling of "goosebumps on the skin." Also, regular overdose cause dysfunction of liver and kidneys, increase the level of ammonia in the body. Minor overdose of the substance cause allergic reactions, nervousness, disorder of digestion and blood thickening.

Food sources

Valin is an indispensable amino acid, which means that there is an urgent need for replenishment of substances with food.

In the high concentration of the amino acid contained in the products:

• animal Origin: Meat (beef, lamb, pork, chicken), Fish, squid, dairy products, different types cheese;
• vegetable origin: lentils, peanuts, soybean, mushrooms, sesame seeds and pumpkins, greens, whole grains, beans, corn flour, peas, beans, sea cabbage.

Using dairy products and eggs it is easy to get a daily dose of valine. The highest concentration of the substance is in cottage cheese, natural yogurt, in the cheese (swiss, melted, goat, Edam), as well as in milk and eggs. Among the seeds and nuts, the most benefits will bring pistachios, cashews, almonds, sesame, as well as sunflower seeds. The choice among fish varieties is better to stop on salmon, trout, a halotus, and among the rich legs of legumes - to choose beans, lentil or chick. White mushrooms and cherries, as well as wild rice, millet, buckwheat and barley - perfect option For vegetarians. But still, perhaps, the valine from quail eggs and walnuts is asleep.

Interaction with other substances

Did you decide to take valine in the form of a food biodendering? Then it is important to know the rules of use and combinations of amino acids in order to get the most out of favor.

The first and most important thing: Valin should always be taken in combination with two other amino acids - leucine and isoleucine. Perfect balance: 2 mg of leucine and valine per milligrams of isoleucine.

The second, which should not be forgotten: on the way to the hematorencephalic barrier, Valin competes with and. This means that the higher the valine level in the body, the less tyrosine and tryptophan contains in brain cells. Considering these amino acid "competitions", tickling tyrosine and tryptophan needed no earlier than an hour before or after receiving the valine.

Third Council. This amino acid is perfectly combined with polyunsaturated fatty acids and "correct" (cereals, muesli, coarse grinding products).

And the fourth rule of the combination of useful substances. Vallan deficiency complicates the absorption of all other amino acids necessary for the body.

Adhering to these tips, you can not worry about the possible deficiency of the valine.

2-amino-3-methylbutan acid

Chemical properties

Valin - widespread aliphatic alpha-amino acid is one of 20 proteinogenic essential amino acids . The connection was first allocated from casina In 1901, Chemik E. Fisher.

Chemical formula Valina: HO2CCH (NH2) CH (CH3) 2, Racea formula Valina: C5H11NO2. . Molecular weight of the compound \u003d 117.15 grams per mol, the density of the substance is 1.230 grams per MS3. Structural formula Valina is considered in detail in the Wikipedia article. The tool has 2 spatial isomes D and L. synthesized amino acid in the form of colorless crystals. L-Valin It is well soluble in water, aqueous solutions of alkalis, poorly dissolved in organic solutions.

Synthesize the substance can be action NH3 on the alpha Bromozovalerian Acid . Since 1982, the tool is produced around the world, about 150 tons per year. The living organism of the amino acid is one of the main components involved in the processes of growth and synthesis of alive tissues, increases muscle coordination and reduces the sensitivity of the body to pain and other unfavorable environmental factors. The main sources of the valine are: chicken, salmon and beef meat; Cow's milk, eggs, walnuts; Wheat and corn flour; Peas and crude rice.

pharmachologic effect

Metabolic.

Pharmacodynamics and pharmacokinetics

This amino acid plays a key role in the processes of synthesis and growth of body tissues, is the source of muscle cell energy, prevents the level and development. The substance significantly improves the quality of muscle coordination and reduces the sensitivity of the body to cold, heat, more and stress. Remedy has the ability to protect myelinic shell - an important part of the nerve fibers of the head and spinal cord. This substance is necessary for the body to maintain normal nitrogen exchange.

Maximum its effectiveness reaches in combination with and. This amino acid Indispensable, that is, the body cannot synthesize it independently. Finding into systemic blood flow The substance is completely metabolized, does not accumulate in tissues.

Indications for use

Amino acid Valin is prescribed in combination with other drugs:

• to provide parenteral nutrition ;
• as a preventive and therapeutic agent with intensive loss of proteins;
• in case of injury, burns, sepsis and peritonite ;
• after extensive operational interventions;
• as part of the complex treatment of inflammatory bowel disease and gastrointestinal tract;
• for depression , addiction, scarm sclerosis ;
• as a prophylactic agent with increased physical exertion.

Contraindications

Means contraindicated:

• with violations of processes metabolism of amino acids ;
• patients with on this substance;
• with severe renal failure or Hyperhydration ;
• patient S. metabolic acidosis .

Side effects

The amino acid valine is usually well tolerated, the adverse reactions occur extremely rarely. Allergic reactions may develop.

Valin, application instructions (method and dosage)

Depending on the dosage form and the purpose, various types of treatment with valine preparations are used. Dosage and duration of reception determines the attending physician.

Overdose

Not described by data overdose by this means.

Interaction

This amino acid can be combined with almost all medicines.

Terms of sale

The recipe is not required.

special instructions

Infusion of preparations containing amino acid is recommended to produce slowly to increase the effectiveness of therapy.

In renal failure, the dosage correction may be required.

During pregnancy and lactation

The drug can be taken during pregnancy and during periods of lactation.

Preparations containing (analogs)

Coincidences on the ATX 4 level code:

Medicines, which contains amino acid Valin: Aminovene , L-Valin , Aminoplasmal B. Brown E 10 , Aminovene infant , Cabward , Aminosol neo, Aminoplasmal E. , Aminosteril , , Moriamin , Nephoratete , Nutriflex , Cerebrolizat. , Hymix .

Price Valline where to buy

Cost of preparation Infrared It is about 3,500 rubles for 10 bottles, with a capacity of 150 ml. You can purchase an amino acid in industrial packaging about 700 rubles, 200 grams.

L-Valin - This is an indispensable amino acid, which is contained in high concentrations in muscle tissue. The body itself almost does not produce it, which means that the body should receive L-Valin From outside, from food or food additives. If you are sitting on a hard diet or every day work hard in gym, fit worry about not to start losing muscular weight. L-Valin Plays a key role in such processes as: - growth and restoration of muscles; - metabolism; - replenishment of energy reserves.

L-valine as a product

L-Vallin is perfect for any person who complies with an active lifestyle. It is quickly absorbed and immediately delivered straight to muscular fabricwhere it promotes healthy metabolism and rapid recovery. L-Valin is quite simple and at the same time a very effective food additive that will help you to achieve your goal. This amino acid is useful not only to people who regularly play sports, but also everyone else, therefore It is worth thinking about including it in your diet. Since this amino acid is not produced by the body, it is very simple and very simple to face its deficit. And L-Valin helps the body not only to cope with workouts, but also transfer the load of the day, reduce stress and avoid fatigue. In small doses, L-Valin is contained in products such as fish, nuts, sesame seeds, lentils, cheese.

Time of receipt

If you want to fully reveal the potential of L-valine, take it simultaneously with L-leucine and L-isoleucin in proportion 2: 2: 1. All three of these amino acids make up a single chain that works most effectively in a team. L-Vallan stands up to, during or after training.

Harm and side effects

Until now, it is not known an overdose cases by this drug, however carefully read the instructions on the package and follow the recommendations.